The real answer is Frank Burns from M*A*S*H, but:
I hated Izzy Stevens before you did. It is not too terribly far from the truth to suggest that this chick ruined Grey’s Anatomy for me. While she had a couple of decent Doctor Moments, she was generally a train wreck of bad decisions. She whined, she fell in love with a patient, she made people around her dumber.
And OMG, the Katherine Heigl drama. Between the saying one damned thing about Isaiah Washington and withdrawing her name from the Emmys, and this season submitting her name to the Emmys. Ugh.
Remember when Shannen Doherty was on 90210 and the line blurred between disliking her and disliking her character until we wanted to spit every time we saw her face? It’s like that.